Search results for " Uterine Neoplasms"

showing 4 items of 4 documents

Alcohol consumption and risk of uterine myoma: A systematic review and meta analysis

2017

Background The published data about alcohol consumption and uterine myoma are scanty and controversial: some studies found positive association whereas other studies showed no association. Objectives To conduct a systematic review and meta-analysis to determine whether alcohol is a risk factor for myoma. Search strategy A MEDLINE/EMBASE search was carried out, supplemented by manual searches of bibliographies of the selected studies. Selection criteria Articles published as full-length papers in English. In the review we included all identified studies. Otherwise, the inclusion criteria for studies included in the meta-analysis were: a) case-control or cohort studies, reporting original dat…

Adult Alcohol Drinking Female Humans Middle Aged Myoma Odds Ratio Risk Factors Uterine Neoplasms Young Adultlcsh:MedicineSocial SciencesBiochemistryCohort StudiesMathematical and Statistical Techniques0302 clinical medicineRisk FactorsOdds RatioMedicine and Health SciencesPsychologyMedicinePublic and Occupational Health030212 general & internal medicinelcsh:Scienceeducation.field_of_studyAlcohol Consumption030219 obstetrics & reproductive medicineMultidisciplinaryObstetricsAlcoholic BeveragesBeerMiddle AgedResearch AssessmentAlcoholismSystematic reviewResearch DesignMeta-analysisUterine NeoplasmsPhysical SciencesFemaleStatistics (Mathematics)Research ArticleCohort studyAdultmedicine.medical_specialtyAlcohol DrinkingSystematic ReviewsSubstance-Related DisordersPopulationAddictionSubgroup analysisResearch and Analysis MethodsBeveragesYoung Adult03 medical and health sciencesMental Health and PsychiatryHumansStatistical MethodsRisk factoreducationNutritionbusiness.industrylcsh:RBiology and Life SciencesEstrogensMyomaOdds ratiomedicine.diseaseMyomaHormonesDietlcsh:QbusinessMathematicsMeta-AnalysisPLOS ONE
researchProduct

Hysteroscopic Evaluation of Endometrial Changes in Breast Cancer Women with or without Hormone Therapies: Results from a Large Multicenter Cohort Stu…

2020

ABSTRACT Study Objective The primary aim of our study was to investigate the incidence of endometrial pathologies, especially endometrial cancer, in women with breast cancer treated with tamoxifen (TAM), aromatase inhibitors (AIs), or receiving no treatment (NT). The secondary aim was to identify, in this cohort, ultrasonographic findings that represent robust indications for hysteroscopy and endometrial biopsy, to avoid unnecessary second-level diagnostic procedures. Design Multicenter retrospective cohort study (Clinical Trial ID: NCT03898947). Setting Data were collected from different Italian centers: Regina Elena National Cancer Institute of Rome, Arbor Vitae Centre of Rome, Gaetano Ma…

BiopsyAromatase inhibitors Breast cancer Endometrial cancer Endometrial pathologies Tamoxifen Adult Aged Aged 80 and over Antineoplastic Agents Hormonal Biopsy Breast Neoplasms Cohort Studies Endometrial Hyperplasia Endometrial Neoplasms Endometrium Female Humans Hysteroscopy Incidence Middle Aged Polyps Precancerous Conditions Pregnancy Retrospective Studies Tamoxifen Uterine Diseases Uterine NeoplasmsCohort StudiesEndometrium0302 clinical medicineBreast cancerEndometrial cancerPregnancyAromatase inhibitors; Breast cancer; Endometrial cancer; Endometrial pathologies; TamoxifenAged 80 and overUterine Diseases030219 obstetrics & reproductive medicinemedicine.diagnostic_testEndometrial pathologiesIncidenceObstetrics and GynecologyMiddle AgedAromatase inhibitorsHysteroscopy030220 oncology & carcinogenesisEndometrial HyperplasiaUterine NeoplasmsFemalemedicine.drugAromatase inhibitors Breast cancer Endometrial cancer Endometrial pathologies TamoxifenAdultmedicine.medical_specialtyAntineoplastic Agents HormonalBreast NeoplasmsHysteroscopy03 medical and health sciencesBreast cancerPolypsmedicineEndometrial PolypHumansAgedRetrospective StudiesGynecologybusiness.industryEndometrial cancerCancerRetrospective cohort studymedicine.diseaseEndometrial NeoplasmsTamoxifenbusinessPrecancerous ConditionsTamoxifenEndometrial biopsy
researchProduct

Out-of-the-box pelvic surgery including iliopsoas resection for recurrent gynecological malignancies: Does that make sense? A single-institution case…

2017

Abstract Objective To report morbidity and oncological outcomes in a consecutive series of lateral isolated recurrent gynecological cancer involving the pelvic side wall (PSW) including the iliopsoas muscle. Material and methods We retrospectively evaluated a consecutive series between 6/2013 and 12/2015 of lateral isolated recurrent gynecological malignancies treated with a lateral endopelvic resection (LEPR). LEPR was defined as an en-bloc lateral resection of a pelvic tumor with sidewall muscle, and/or bone, and/or major nerve, and/or major vascular structure. Post-surgical complications, quality of life (QoL) and survivals were computed. Results Seventy-four women with pelvic isolated r…

Pelvic NeoplasmPsoas MusclePostoperative Complications0302 clinical medicineQuality of lifeRetrospective StudieUterine NeoplasmPelvic Neoplasms030212 general & internal medicineIliopsoas resection; Lateral endopelvic resection; Pelvic side wall disease; Recurrent gynecological malignanciesPelvic NeoplasmsPsoas MusclesOvarian NeoplasmsPelvic side wall diseaseGraft Occlusion VascularPeripheral Nervous System DiseasesIliopsoas resectionGeneral MedicineMiddle AgedThrombosisCompartment SyndromeTreatment OutcomeOncology030220 oncology & carcinogenesisUterine NeoplasmsThrombosiFemaleIliopsoasHumanAdultmedicine.medical_specialtyIliopsoas MuscleIliopsoas resection; Lateral endopelvic resection; Pelvic side wall disease; Recurrent gynecological malignancies; Adult; Aged; Compartment Syndromes; Disease-Free Survival; Female; Graft Occlusion Vascular; Humans; Middle Aged; Muscle Skeletal; Neoplasm Recurrence Local; Ovarian Neoplasms; Pelvic Neoplasms; Peripheral Nervous System Diseases; Postoperative Complications; Psoas Muscles; Quality of Life; Retrospective Studies; Thrombosis; Treatment Outcome; Uterine Neoplasms; Surgery; OncologyCompartment SyndromesDisease-Free Survival03 medical and health sciencesmedicineHumansMuscle SkeletalRetrospective StudiesAgedbusiness.industryOvarian NeoplasmThrombosisRetrospective cohort studyPerioperativeRecurrent gynecological malignanciemedicine.diseaseSurgerySettore MED/40 - GINECOLOGIA E OSTETRICIAQuality of LifeLateral endopelvic resectionPelvic tumorSurgeryPostoperative ComplicationRecurrent gynecological malignanciesNeoplasm Recurrence LocalPeripheral Nervous System DiseasebusinessEuropean Journal of Surgical Oncology (EJSO)
researchProduct

Optimized culture conditions for tissue explants of uterine leiomyoma

2012

Background Uterine leiomyomas are the most common benign tumours in women, which arise from smooth muscle cells of the uterine myometrium and usually are multicentric. In spite of their frequency pathogenesis is widely unknown, mainly due to the absence of a suitable model system. We describe the systematic optimization of culturing leiomyoma tissue explants in an economical and effective ex vivo system. Methods Different concentrations of oxygen, different media, sera, hormones, and growth factor supplements were tested. Immunohistochemical stainings with antibodies against hormone receptors as well as specifying proliferation and apoptotic indices and real-time PCR were performed. Results…

medicine.medical_treatmentCulture Media; Epidermal Growth Factor; Estradiol; Female; Humans; Immunohistochemistry; Leiomyoma; Progesterone; RNA Messenger; Real-Time Polymerase Chain Reaction; Uterine NeoplasmsBiologyReal-Time Polymerase Chain ReactionGeneral Biochemistry Genetics and Molecular BiologyAndrologyTissue culturemedicineHumansRNA MessengerUterine NeoplasmProgesteroneUterine leiomyomaEpidermal Growth FactorEstradiolLeiomyomaGrowth factorMyometriummedicine.diseaseImmunohistochemistrySettore MED/40 - Ginecologia E OstetriciaCulture MediaLeiomyomaHormone receptorUterine NeoplasmsFemaleEx vivoHuman
researchProduct